Sewer line replacement in NYC typically costs between $10,000 and $25,000 for a standard residential property, though prices can range from $5,000 for simple repairs to over $50,000 for complex commercial projects. The cost depends on several key factors including the length of pipe being replaced, depth of the sewer line, pipe material chosen, soil conditions, street restoration requirements, and permit fees. Manhattan projects tend to be the most expensive due to dense underground infrastructure and higher labor costs, while Staten Island projects may be more affordable due to easier access. NYC DEP permits typically cost $1,000-$3,000, and DOT street opening permits add another $1,500-$5,000 depending on the street classification. Trenchless methods like pipe lining or pipe bursting can sometimes reduce costs by 20-40% compared to traditional excavation.